CELEBRATING 20 YEARS OF TRANSFORMATIVE STEM CELL RESEARCH
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Microscopy image of a human stem cell–derived hippocampal organoid with inhibitory neurons in red
Slices of mini–brain organoids with neural stem cells (red) and cortical neurons (green)
A microscope image of a mini brain organoid showing layered neural tissue and different types of neural cells.
Image showing brain cells with lower levels of Foxp1 function (at left) and higher levels (right). Apical radial glia are stained in green and secondary progenitors and neurons stained in red.
Clockwise from top left: Luisa Iruela-Arispe, Dr. S. Thomas Carmichael, Dr. Inma Cobos, William Lowry, Kathrin Plath and Bennett Novitch.
Left: Olig2 expression (blue) results in reduced Hes gene expression (red) and increased motor neuron formation (green) in the developing mouse spinal cord. Right: in the absence of Olig2, Hes expression increases and motor neuron formation decreases.
Microscopic image of a mini brain organoid, showing layered neural tissue and different groups of neural stem cells (in blue, red and magenta) giving rise to neurons (green).