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Andrew Goldstein is an assistant professor in residence in the UCLA departments of Urology and Molecular, Cell and Developmental Biology, as well as a member of the Broad Stem Cell Research Center and Jonsson Comprehensive Cancer Center, both at UCLA.
T cells (red) produced using artificial thymic organoids developed at UCLA.
Evangelina Vaccaro received Dr. Kohn’s treatment for bubble baby disease in 2012.
Evangelina Vaccaro (far right), who received Dr. Kohn’s treatment for bubble baby disease in 2012, with her family before her first day of school.
Left to right: Zika virus (green) infects and destroys the formation of neurons (pink) in human stem cell-derived brain organoids. Administration of 25HC blocks Zika infection and preserves neuron formation in the organoids. Reduced brain size and structure in a Zika-infected mouse brain. Administration of 25HC preserves mouse brain size and structure.
At left, head and neck squamous cell carcinoma invasive growth, and at right, cancer stem cells (shown in red) in head and neck squamous cell carcinoma.
The three Broad Stem Cell Research Center directors thank Eli & Edythe Broad for their visionary philanthropy. From left: Owen Witte, Eli Broad, Edythe Broad, Arnold Kriegstein and Andy McMahon
The new protocol turned 90 percent of human pluripotent stem cells into somite cells in just four days; those somite cells then generated (left to right) cartilage, bone and muscle cells.
From left: senior authors Kathrin Plath and Jason Ernst and first authors Petko Fiziev and Constantinos Chronis