Refers to a therapeutic product that is specifically formulated for or customized to a particular patient. In patient-specificRefers to a therapeutic product that is specifically formulated for or customized to a particular patient. In patient-specific cell therapies, a patient's cells are either genetically engineered, expanded or reprogrammed and differentiated to produce cells that same patient needs for treatment.patient-specificRefers to a therapeutic product that is specifically formulated for or customized to a particular patient. In patient-specific cell therapies, a patient's cells are either genetically engineered, expanded or reprogrammed and differentiated to produce cells that same patient needs for treatment. cell therapies, a patient's cells are either genetically engineered, expanded or reprogrammed and differentiated to produce cells that same patient needs for treatment.
The capacity some cells have to switch from one cell type to another and — in some cases — back again. The plasticityThe capacity some cells have to switch from one cell type to another and — in some cases — back again. The plasticity of certain tissue-specific stem cells enables them to transform into cell types that would normally be considered outside their normal range of differentiation.plasticityThe capacity some cells have to switch from one cell type to another and — in some cases — back again. The plasticity of certain tissue-specific stem cells enables them to transform into cell types that would normally be considered outside their normal range of differentiation. of certain tissue-specific stem cellsMature stem cells that are found in many adult organs and tissues (such as the brain and muscles). Unlike pluripotent stem cells, they can only produce the cell types found in the organ or tissue they inhabit. They're responsible for replacing cells that have been lost due to natural wear and tear, injury and illness throughout life; however, their ability to do so decreases with age.tissue-specific stem cellsMature stem cells that are found in many adult organs and tissues (such as the brain and muscles). Unlike pluripotent stem cells, they can only produce the cell types found in the organ or tissue they inhabit. They're responsible for replacing cells that have been lost due to natural wear and tear, injury and illness throughout life; however, their ability to do so decreases with age. enables them to transform into cell types that would normally be considered outside their normal range of differentiationThe process by which stem cells transform into specific, specialized cell types with distinct functions and features.differentiationThe process by which stem cells transform into specific, specialized cell types with distinct functions and features..
Stem cellsCells that have the ability to differentiate into multiple types of cells and make an unlimited number of copies of themselves.Stem cellsCells that have the ability to differentiate into multiple types of cells and make an unlimited number of copies of themselves. that can undergo self-renewalWhen stem cells self-renew, they divide to make identical copies of themselves.self-renewalWhen stem cells self-renew, they divide to make identical copies of themselves. and differentiationThe process by which stem cells transform into specific, specialized cell types with distinct functions and features.differentiationThe process by which stem cells transform into specific, specialized cell types with distinct functions and features. to become any cell type found in the body. The two major types used in research are embryonic stem cellsPluripotent stem cells that give rise to every cell type in the adult body. They are derived from the inner cell mass of a blastocyst.embryonic stem cellsPluripotent stem cells that give rise to every cell type in the adult body. They are derived from the inner cell mass of a blastocyst. and induced pluripotent stem cellsiPSCs are adult cells — typically skin or blood — that have been reprogrammed in the lab to behave like stem cells, giving them the potential to become any of the cell types found in all major tissues in the body. Because they are made from a patient's own cells, they carry that person's unique genetic code, making them a powerful tool for disease research and personalized medicineinduced pluripotent stem cellsiPSCs are adult cells — typically skin or blood — that have been reprogrammed in the lab to behave like stem cells, giving them the potential to become any of the cell types found in all major tissues in the body. Because they are made from a patient's own cells, they carry that person's unique genetic code, making them a powerful tool for disease research and personalized medicine.
Descendants of stem cellsCells that have the ability to differentiate into multiple types of cells and make an unlimited number of copies of themselves.stem cellsCells that have the ability to differentiate into multiple types of cells and make an unlimited number of copies of themselves. that can further differentiate to produce one or more specialized cell types. They are more limited than pluripotent stem cellsStem cells that can undergo self-renewal and differentiation to become any cell type found in the body. The two major types used in research are embryonic stem cells and induced pluripotent stem cells.pluripotent stem cellsStem cells that can undergo self-renewal and differentiation to become any cell type found in the body. The two major types used in research are embryonic stem cells and induced pluripotent stem cells. in that they cannot self-renew indefinitely and can only produce a limited range of specific cell types. For example, neural progenitor cellsDescendants of stem cells that can further differentiate to produce one or more specialized cell types. They are more limited than pluripotent stem cells in that they cannot self-renew indefinitely and can only produce a limited range of specific cell types. For example, neural progenitor cells can only produce neurons.progenitor cellsDescendants of stem cells that can further differentiate to produce one or more specialized cell types. They are more limited than pluripotent stem cells in that they cannot self-renew indefinitely and can only produce a limited range of specific cell types. For example, neural progenitor cells can only produce neurons. can only produce neurons.