Mina S. Sedrak, M.D.

Associate Professor, Medicine

MSedrak@mednet.ucla.edu

Director, Cancer and Aging Program, UCLA Health Jonsson Comprehensive Cancer Center

Research Areas

Aging & Healthspan Cancer & Immunotherapy

Mina S. Sedrak, M.D., is a medical oncologist specializing in the care of older adults with breast cancer. His research explores the complex relationship between cancer and aging, with a specific focus on developing therapies that enable older cancer patients and survivors to lead longer, healthier and more vibrant lives.

Sedrak explores the impact of cancer treatments on aging processes, such as cellular senescence, and develops interventions that can mitigate treatment-related accelerated aging to improve the population health of cancer patients and survivors.

With extensive experience studying the effects of cancer therapy on aging outcomes, Sedrak collaborates with experts across disciplines to develop geroscience-informed interventions. He actively recruits older cancer patients and survivors to innovative clinical trials that aim to translate basic science discoveries from the lab to the bedside. He is deeply committed to translating scientific discoveries into practical solutions that can positively impact patients' lives.

Sedrak's leadership extends to national organizations, where he contributes to shaping the agenda for cancer and aging research. His collaborative spirit and dedication to improving care for older adults with cancer continue to drive progress in the field. In addition to advancing cancer and aging research, Sedrak is dedicated to mentoring the next generation of geriatric oncology researchers in geroscience, ensuring a well-trained cadre is poised to lead the field in the future.

"As the number of breast cancer survivors rises dramatically — estimated to reach more than 6 million by 2040 — mitigating chemotherapy-induced accelerated aging is an urgent public health issue."

Mina S. Sedrak, M.D.

Associate Professor, Medicine

Investigating the pathogenesis of treatment-induced accelerated aging in cancer survivors and establishing interventions to mitigate the associated health consequences
Examining how exercise and certain drugs may be able to slow chemotherapy-related accelerated aging in breast cancer survivors
Developing tools to phenotype cancer survivors at risk for treatment-induced accelerated aging