High Throughput Sequencing

DNA sequencing is an indispensable tool that has assisted in the significant acceleration of biological research and discovery. The BSCRC HTS facility provides the UCLA stem cell research community with access to the “next generation” DNA sequencing technology. The center features one Illumina HiSeq 2500 and three Illumina HiSeq 2000 sequencing instruments which generate a large amount of DNA sequences with high accuracy in a relatively short time. The HTS facility offers exciting capabilities including SNP mapping, RNA expression measurements, ChIP-seq, and DNA Methylation analyses at a genomewide scale. Such capabilities enable researchers to study the regulation of thousands of genes in a single experiment, providing unprecedented insights into the molecular biology of a cell.