PTPσ inhibitors promote hematopoietic stem cell regeneration

Yurun Zhang, Martina Roos, Heather Himburg, Christina M. Termini, Mamle Quarmyne, Michelle Li, Liman Zhao, Jenny Kan, Tiancheng Fang, Xiao Yan, Katherine Pohl, Emelyne Diers, Hyo Jin Gim, Robert Damoiseaux, Julian Whitelegge, William McBride, Michael E. Jung and John P. Chute.

Wednesday, August 14, 2019
Published in Nature Communications
Bone marrow showing a loss of blood cells in mice after radiation (left) and then after treatment with the PTP-sigma inhibitor (right), where the recovery of blood cells is visible.