Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents

Irene L. Llorente,Yuan Xie, Jose A. Mazzitelli, Emily A. Hatanaka, Jessica Cinkornpumin, David R. Miller, Ying Lin, William E. Lowry, and 
S. Thomas Carmichael

Wednesday, April 21, 2021
Published in Science Translational Medicine
Microscope images showing brain tissue that has been damaged by white matter stroke (left) and then repaired by the new glial cell therapy (right). Myelin (seen in red), is a substance that protects the connections between neurons and is lost due to white matter stroke. As seen at right, the glial cell therapy (green) restores lost myelin and improves connections in the brain. | Credit: UCLA Broad Stem Cell Research Center/Science Translational Medicine