Mapping human haematopoietic stem cells from haemogenic endothelium to birth

Vincenzo Calvanese, Sandra Capellera-Garcia, Feiyang Ma, Iman Fares, Simone Liebscher, Elizabeth S. Ng, Sophia Ekstrand, Júlia Aguadé-Gorgorió, Anastasia Vavilina, Diane Lefaudeux, Brian Nadel, Jacky Y. Li, Yanling Wang, Lydia K. Lee, Reza Ardehali, M. Luisa Iruela-Arispe, Matteo Pellegrini, Ed G. Stanley, Andrew G. Elefanty, Katja Schenke-Layland & Hanna K. A. Mikkola

Wednesday, April 13, 2022
Published in Nature
blood stem cells
Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. UCLA scientists’ confirmation of this process clarifies a longstanding controversy about the stem cells’ cellular origin. | Credit: Hanna Mikkola Lab/UCLA, Katja Schenke-Layland Lab/University of Tübingen, Nature