Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin

A. Flores, S. Sandoval-Gonzalez, R. Takahashi, A. Krall, L. Sathe, L. Wei, C. Radu, J. Jolly, N. Graham, H. R. Christofk and W. E. Lowry. 

Thursday, January 10, 2019
Published in Nature Communications
Image shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production blocked (left) grew at the same rate as the tumor with normal lactate production (right).