Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis

Haruko Nakano, Itsunari Minami, Daniel Braas, Herman Pappoe, Xiuju Wu, Addelynn Sagadevan, Laurent Vergnes, Kai Fu, Marco Morselli, Christopher Dunham, Xueqin Ding, Adam Z Stieg, James K Gimzewski, Matteo Pellegrini, Peter M Clark, Karen Reue, Aldons J Lusis, Bernard Ribalet, Siavash K Kurdistani, Heather Christofk, Norio Nakatsuji and Atsushi Nakano

Tuesday, December 12, 2017
Published in eLife
https://elifesciences.org/articles/29330
Human heart cells grown from stem cells show less robust muscle fibers (green) in high glucose conditions (left) compared to reduced glucose conditions (right).