Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis
Haruko Nakano, Itsunari Minami, Daniel Braas, Herman Pappoe, Xiuju Wu, Addelynn Sagadevan, Laurent Vergnes, Kai Fu, Marco Morselli, Christopher Dunham, Xueqin Ding, Adam Z Stieg, James K Gimzewski, Matteo Pellegrini, Peter M Clark, Karen Reue, Aldons J Lusis, Bernard Ribalet, Siavash K Kurdistani, Heather Christofk, Norio Nakatsuji and Atsushi Nakano
Human heart cells grown from stem cells show less robust muscle fibers (green) in high glucose conditions (left) compared to reduced glucose conditions (right).