Endocardially Derived Macrophages Are Essential for Valvular Remodeling

Ayako Shigeta, Vincent Huang, Jonathan Zuo, Rana Besada, Yasuhiro Nakashima, Yan Lu, Yichen Ding, Matteo Pellegrini, Rajan P. Kulkarni, Tzung Hsiai, Arjun Deb, Bin Zhou, Haruko Nakano and Atsushi Nakano.

Thursday, February 21, 2019
Published in Developmental Cell
Microscopic images of a normal heart valve in a mouse, left, and a heart valve grown in a lab with heart-derived macrophages blocked, right. Without those macrophages, the valves are thick and deformed.