Antoni Ribas, MD, PhD

Antoni Ribas, M.D., Ph.D. 

Professor

Bio

Antoni Ribas, M.D., Ph.D., conducts laboratory and clinical research focused on malignant melanoma, for which few effective therapies exist. He wants to understand how the immune system can be effectively used to fight cancer in order to develop more effective and less toxic therapies for melanoma patients.

His projects include laboratory and clinical translational research in adoptive cell transfer therapy using T-cell receptor engineered lymphocytes designed to seek out melanoma cells. Dr. Ribas also focuses on molecular imaging and advanced monitoring of the immune system to better study how it can fight cancer. He’s also testing, both in the laboratory and the clinic, novel targeted therapies blocking cancer-causing events that result in melanoma, as well as the potential clinical applications of nanoparticle delivery of siRNA, which interferes with gene expression related to cancer.

Dr. Ribas’ interest in creating a cancer-fighting immune system led to his interest in stem cell research. He hopes to genetically engineer stem cells so they can repopulate the immune system with a progeny of killer immune cells to attack the cancer. Dr. Ribas’ goal is to bring new concepts from the laboratory to the clinic to help patients with advanced melanomas.

In addition to his affiliation with the Broad Stem Cell Research Center at UCLA, Dr. Ribas is a member of UCLA’s Jonsson Comprehensive Cancer Center and the cancer center’s Tumor Immunology and Cancer Molecular Imaging program areas. He also is an elected member of the American Society of Clinical Investigation.

A professor of Hematology/Oncology, Dr. Ribas joined the UCLA faculty in 1996 from the Hospital Vall d’Hebron, Autonomous University of Barcelona in Spain, where he earned both his medical and doctoral degrees.

Dr. Ribas’ work is funded by the California Institute for Regenerative Medicine (CIRM), the National Institutes of Health (NIH) and the Caltech-UCLA Joint Center for Translational Medicine (JCTM).

Publications

Clinical Trials