UCLA researchers at the Orthopaedic Hospital Research Center and Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research (Broad Stem Cell Research Center or BSCRC) led by Bruno Péault, UCLA professor of orthopedic surgery and member of the BSCRC and of the Scottish Center for Regenerative Medicine (Edinburgh, UK), have refined a specific component of mesenchymal (bone marrow) stem cells (MSCs) called perivascular cells that support the maintenance of hematopoietic (blood) stem and progenitor cells (HSPCs), dramatically improving scientists’ capabilities for sustaining ex vivo high-quality HSPCs, which are capable of becoming any kind of blood cell. This dramatic discovery in the function of how blood stem cells develop and survive in the body could lead scientists to better understanding and treatment of blood diseases such as leukemia. The study was published online ahead of press today in Blood.