Arnold Chin, MD, PhD
Arnold Chin, MD, PhD, is a physician-scientist dedicated to improving the lives of patients with urologic malignancies. Focused on bladder and prostate cancer, his research team studies how the immune system recognizes and modulates cancer growth, invasion and metastases, using both animal models as well as tumors from his patients.
Current projects include understanding the mechanisms that distinct immune pathways use to regulate tumor growth and spread, which will be important in identifying targets for novel immune-based therapies. A second area is focused on understanding bladder cancer stem cells, which may be the origin of the cancer, with failure in eliminating these cells resulting in cancer recurrence and spread. Targeting the cancer stem cell population, the team is developing a personalized therapy program for bladder cancer patients, taking tissues from individuals and testing them for genetic markers and sensitivity to various therapies.
Dr. Chin hopes his studies will determine which tumors may respond to specific treatments and design novel therapeutics that optimize the body’s own immune system to fight cancer.
In addition to being a member of the Broad Stem Cell Research Center at UCLA, Dr. Chin is also a member of UCLA’s Jonsson Comprehensive Cancer Center, UCLA’s Institute of Urologic Oncology, the American Association for Cancer Research and the American Urological Association.
An Assistant Professor of Urology, Dr. Chin came to UCLA in 1995 when he enrolled in the Medical Scientist Training Program, which combines medical and doctoral degree work. He subsequently completed his residency training in urology at UCLA. Chin graduated from Princeton University with a degree in chemistry in 1995.
Dr. Chin’s work is funded by STOP Cancer, the Oppenheimer Foundation, the American Association of Cancer Research, the stem cell center’s UCLA Scholars in Translational Medicine Program and the Department of Defense.