All BSCRC Videos

CIRM Video: Alpha Stem Cell Clinics 

In late May, three Network programs from UCSD, City of Hope, and the UCLA/UCI consortium joined CIRM at the City of Hope campus for a kickoff workshop to mark the beginning of the Alpha Stem Cell Clinics endeavor, a $24 million initiative to provide the infrastructure necessary to get stem cell clinical trials off the ground in the most efficient manner possible.

"Let there Be Tiny Miracles" 

Celebrating the launch of The Centennial Campaign for UCLA, this video offers a glimpse into the miraculous work of Broad Stem Cell Research Center faculty member Dr. Donald B. Kohn and his impactful research to cure blood diseases.

Gene Therapy Cure for 18 ‘Bubble Baby’ Patients

Researchers at UCLA announced today that they had cured 18 children who were born with the so-called Bubble Baby disease, a genetic disorder that leaves the young sufferers without a working immune system, putting them at risk of death from infections, even the common cold.

Stem Cell Cure for "Bubble Baby" Disease, Pioneered by UCLA's Don Kohn

On November 18th, 2014, a UCLA research team led by Donald Kohn, M.D., announced a breakthrough gene therapy and stem cell cure for "bubble baby" disease, or severe combined immunodefiency (SCID). Babies born with SCID lack an immune system and have no ability to fight off infections so even a minor cold could be deadly.

UCLA Researchers Seek New Treatments for "Bubble Boy" Disease

In this KCAL 9 News segment, Dr. Donald Kohn talks about how UCLA scientists are utilizing gene therapy to help children with so called "bubble boy" disease, or SCID (Severe Combined Immunodeficiency Disease). This breakthrough research could have a huge impact on future therapies and treatments.

Defeating Sickle Cell Disease with Stem Cells + Gene Therapy

Using a mix of science, humor and easy to understand language, this video describes sickle cell disease and a CIRM-funded clinical trial at UCLA that is testing a stem cell and gene therapy cure. This awful genetic disorder causes red blood cells to assume a sickle shape, clogging blood vessels and producing episodes of excruciating pain, called crises, and leading to progressive organ damage. If all goes well, the human suffering due to sickle cell disease may soon be a thing of the past. This trial is one of the first to be part of CIRM's Alpha Stem Cell Clinic Network.

The Squishiness of Cancer Cells

How squishy are your cells? Corrupted, cancerous cells have a different texture than healthy cells. They're softer and more malleable, or as UCLA's Amy Rowat puts it, more "squishy." Her research investigates the texture of cells in our body, which can have a huge impact on treatments for cancer and genetic disorders.

Jonathan Lam Wins CIRM Elevator Speech Challenge

Jonathan Lam who conducts research in the laboratory of Dr. Tatiana Segura (UCLA Chemical & Biochemical Engineering Department) won first place in the non-lead scientist category for his elevator pitch describing his research focus of developing a therapy to promote wound healing in the brain after a stroke.

CIRM Elevator Speech Challenge: Drs. Miceli and Nelson

Drs. Carrie Miceli and Stan Nelson discuss their personal commitment to studying Duchenne Muscular Dystrophy for which there are no effective therapies. The husband and wife research team's son is diagnosed with the disease. This video pitch received honorable mention and the judges "loved their [Miceli's and Stan's] commitment" to their scientific research.

CIRM Elevator Speech Challenge: Joseph Hargan Calvopina

UCLA BSCRC-CIRM predoctoral trainee, Joseph Hargan Calvopina conducts research in the laboratory of Dr. Amander Clark (Molecular, Cell & Developmental Biology). Calvopina received honorable mention for discussing the use of stem cells to understand the nuts and bolts of how human DNA passes from one generation to the next.

CIRM Elevator Speech Challenge: Dr. Andrew Goldstein

Dr. Andrew Goldstein received honorable mention for his CIRM Elevator Speech video which highlights his work to better understand resistant cancer cells which survive and regrow as tumor(s). He is hopeful that uncovering characteristics about the resilience of prostate cancer cells may inform our understanding of many other types of cancer as well.

CIRM Elevator Speech Challenge: William Kim

UCLA BSCRC-CIRM predoctoral trainee, William Kim conducts research in the laboratory of Dr. Gay Crooks (Pathology & Laboratory Medicine). In this video, which received honorable mention, Kim discusses the ability to create red blood cells from human embryonic stem cells in hopes to create an unlimited, universal supply for blood transfusions.

Dr. Donald Kohn Discusses Stem Cell Research Breakthrough for Sickle Cell Disease

Dr. Donald Kohn, researcher at the Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and Jonsson Comprehensive Cancer Center researcher, discusses a new breakthrough in stem cell research for sickle cell disease, and translating basic science discoveries to treatment.

8th Annual Stem Cell Symposium

The 8th Annual Stem Cell Symposium “Stem Cells and Cancer: Shared Paths, Different Destinations” was held on February 10, 2012 on the UCLA campus and featured leading scientists from prestigious U.S. and international institutions who have made significant contributions to stem cell biology and cancer research.

Beating Heart Muscle Cells

Scientists led by Dr. Hanna Mikkola of the BSCRC at UCLA have generated beating cardiomyocytes, or heart muscle cells, from blood forming tissue.

Researchers discuss Creating HIV-Fighting Stem Cells

Human stem cells can be genetically engineered into HIV-fighting cells, according to a study by scientists with the BSCRC at UCLA, Drs. Scott G. Kitchen and Jerome Zack.

Researchers discuss the Placental Niche

Dr. Hanna Mikkola of the BSCRC at UCLA, and Akanksha Chhabra, a post-doctoral fellow, discuss their discovery of a critical placental niche cell and signaling pathway that prevents blood precursors from premature differentiation in the placenta, a process that is necessary for ensuring proper blood supply for an individual's lifetime.

Researchers Explain Neural Cell Breakthrough

BSCRC researchers explain neural cell breakthrough of being the first to derive potentially clinically usable induced pluripotent stem (iPS) cells and differentiate them into neurons in animal origin-free derivation and differentiation conditions using commercially available reagents to facilitate broad application.

Take a tour of Dr. Heather Christofk's Lab

Dr. Heather Christofk, an assistant professor of Molecular and Medical Pharmacology and a researcher with the BSCRC at UCLA, discusses her research and provides a tour of her lab.

The Next Frontier in Stem Cell Research

UCLA Life Sciences Public Lecture: "The Next Frontier in Stem Cell Research" Amander Clark, PhD March 16, 2011

Bone Marrow Stem Cells and Gene Therapy

UCLA Life Sciences Public Lecture: "Bone Marrow Stem Cells: Developing New Therapies in the Fight Against Disease" Donald Kohn, M.D. January 18, 2011

Innovations in the Life Sciences with Dr. Owen Witte

Dr. Owen Witte, director of the BSCRC at UCLA and a Howard Hughes Medical Institute investigator, discusses cutting edge research and new developments in the life sciences.

Creating Induced Pluripotent Stem Cells

Dr. Jerome Zack, Associate Director, UCLA AIDS Institute, professor of Medicine, Microbiology, Immunology & Molecular Genetics, and researcher with the BSCRC at UCLA discusses creating induced pluripotent stem (iPS) cells.

Creating Embryonic Stem Cell Lines

Dr. Amander Clark, an assistant professor of molecular, cell and developmental biology and a researcher with the BSCRC at UCLA discusses creating human embryonic stem cell (hESC) lines.

Kathrin Plath: Here. Now. UCLA.

Dr. Kathrin Plath, UCLA Biological Chemistry Professor and BSCRC researcher, talks about the incredibly rapid pace of research in the field of embryonic stem cells. Her ground-breaking work has resulted in the transformation of ordinary mouse cells into the equivalent of stem cells.

Stem Cell Research

BSCRC Director Owen Witte, MD and Jonsson Comprehensive Cancer Center Director Judith Gasson, PhD discuss the importance of stem cell research.

UCLA Broad Stem Cell Research Center $20 Million Gift Announcement

The Eli and Edythe Broad Foundation donated $20 million to fund adult and embryonic stem cell research at UCLA, enhancing a program that brings together biologists, chemists, engineers, geneticists and other scientists to develop new and more effective treatments for cancer, HIV/AIDS, Parkinson’s, metabolic disorders and other medical conditions.